Buy Norfloxacin (Noroxin) tablets online

 

How and where to order Noroxin (Norfloxacin) 100, 200, 400 mg tablets or capsules online:

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Sellers:NORFLOXACIN STORES
Prices:from $0.36 per pill
Forms:100 mg, 200 mg, 400 mg tablets
Quantity:30-360 pills
Type:Norfloxacin brand, Noroxin generic
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Delivery:Regular and express mail service
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Indications and usage:

Noroxin (Norfloxacin) is indicated for the treatment of adults with the following infections caused by susceptible strains of the designated microorganisms:

Urinary tract infections

Uncomplicated urinary tract infections (including cystitis) due to Enterococcus faecalis, Escherichia coli, Klebsiella pneumoniae, Proteus mirabilis, Pseudomonas aeruginosa, Staphylococcus epidermidis, Staphylococcus saprophyticus, Citrobacter freundii, Enterobacter aerogenes, Enterobacter cloacae, Proteus vulgaris, Staphylococcus aureus, or Streptococcus agalactiae.

Complicated urinary tract infections due to Enterococcus faecalis, Escherichia coli, Klebsiella pneumoniae, Proteus mirabilis, Pseudomonas aeruginosa, or Serratia marcescens.

Sexually transmitted diseases

Uncomplicated urethral and cervical gonorrhea due to Neisseria gonorrhoeae.

Prostatitis

Prostatitis due to Escherichia coli.

Penicillinase production should have no effect on norfloxacin activity.

Appropriate culture and susceptibility tests should be performed before treatment in order to isolate and identify organisms causing the infection and to determine their susceptibility to norfloxacin. Therapy with norfloxacin may be initiated before results of these tests are known; once results become available, appropriate therapy should be given. Repeat culture and susceptibility testing performed periodically during therapy will provide information not only on the therapeutic effect of the antimicrobial agents but also on the possible emergence of bacterial resistance.

To reduce the development of drug-resistant bacteria and maintain the effectiveness of Noroxin and other antibacterial drugs, Norfloxacin should be used only to treat or prevent infections that are proven or strongly suspected to be caused by susceptible bacteria. W hen culture and susceptibility information are available, they should be considered in selecting or modifying antibacterial therapy. In the absence of such data, local epidemiology and susceptibility patterns may contribute to the empiric selection of therapy.


Contraindications:

Noroxin (Norfloxacin) is contraindicated in persons with a history of hypersensitivity, tendinitis, or tendon rupture associated with the use of norfloxacin or any member of the quinolone group of antimicrobial agents.


Dosage and administration:

Norfloxacin (Noroxin) tablets should be taken at least one hour before or at least two hours after a meal or ingestion of milk and/or other dairy products. Multivitamins, other products containing iron or zinc, antacids containing magnesium and aluminum, sucralfate, or Videx (Didanosine), chewable/buffered tablets or the pediatric powder for oral solution, should not be taken within 2 hours of administration of norfloxacin. Noroxin pills should be taken with a glass of water. Patients receiving this medication should be well hydrated.


Dosage forms and strengths:

Noroxin (Norfloxacin) is available in 400 mg tablets. Each tablet contains the following inactive ingredients: cellulose, croscarmellose sodium, hydroxypropyl cellulose, hydroxypropyl methylcellulose, magnesium stearate, and titanium dioxide.


Overdosage:

No significant lethality was observed in male and female mice and rats at single oral doses of norfloxacin up to 4 g/kg.

In the event of acute overdosage, the stomach should be emptied by inducing vomiting or by gastric lavage, and the patient carefully observed and given symptomatic and supportive treatment. Adequate hydration must be maintained.


Warnings:

  • Tendinopathy and tendon rupture
  • Exacerbation of myasthenia gravis
  • Central nervous system effects/disorders
  • Hypersensitivity reactions
  • Clostridium difficile associated diarrhea
  • Peripheral neuropathy
  • Syphilis treatment


    Precautions:

    Needle-shaped crystals were found in the urine of some volunteers who received either placebo, 800 mg norfloxacin, or 1600 mg norfloxacin (at or twice the recommended daily dose, respectively) while participating in a double-blind, crossover study comparing single doses of norfloxacin with placebo. W hile crystalluria is not expected to occur under usual conditions with a dosage regimen of 400 mg b.i.d., as a precaution, the daily recommended dosage should not be exceeded and the patient should drink sufficient fluids to ensure a proper state of hydration and adequate urinary output.

    Alteration in dosage regimen is necessary for patients with impaired renal function.

    Moderate to severe photosensitivity/phototoxicity reactions, the latter of which may manifest as exaggerated sunburn reactions (e.g., burning, erythema, exudation, vesicles, blistering, edema) involving areas exposed to light (typically the face, "V" area of the neck, extensor surfaces of the forearms, dorsa of the hands), can be associated with the use of quinolone antibiotics after sun or UV light exposure. Therefore, excessive exposure to these sources of light should be avoided. Drug therapy should be discontinued if phototoxicity occurs. Rarely, hemolytic reactions have been reported in patients with latent or actual defects in glucose-6-phosphate dehydrogenase activity who take quinolone antibacterial agents, including norfloxacin. Prescribing Noroxin in the absence of a proven or strongly suspected bacterial infection or a prophylactic indication is unlikely to provide benefit to the patient and increases the risk of the development of drug-resistant bacteria.


    Drug Interactions:

    Some medicines may be affected by norfloxacin, or may affect how well it works. These include:

  • nitrofurantoin, another antibiotic used to treat urinary tract infections
  • erythromycin, an antibiotic used to treat and, in some cases, prevent infections
  • theophylline, a medicine used to treat asthma
  • cyclosporin, a medicine commonly used in patients who have received organ transplants
  • warfarin, a medicine used to stop blood clots
  • glibenclamide, a medicine used to treat diabetes
  • probenecid, a medicine used to treat gout
  • amiodarone, procainamide and sotalol, medicines used to treat irregular heart beats
  • cisapride, a medicine used to treat gastric reflux
  • antipsychotics, a group of medicines used to treat certain mental & emotional conditions
  • tricyclic antidepressants, a group of medicines used to treat depression
  • non-steroidal anti-inflammatory drugs.

    Related medications:

  • Ivermectin (Stromectol)
  • Moxifloxacin (Avelox, Moxicip)

    Your doctor can tell you what to do if you are taking any of these medicines. If you are not sure whether you are taking any of these medicines, check with your doctor, pharmacist, or other healthcare provider.


    Adverse reactions, side effects:

    The most common adverse experiences ( > 1.0%) were:

  • dizziness
  • nausea
  • headache
  • abdominal cramping

    Additional reactions (0.3%-1.0%) were:

  • anorexia
  • diarrhea
  • hyperhidrosis
  • asthenia
  • anal/rectal pain
  • constipation
  • dyspepsia
  • flatulence
  • tingling of the fingers
  • vomiting


    Use in specific populations:

    Pregnancy

    Teratogenic Effects: Norfloxacin has been shown to produce embryonic loss in monkeys when given in doses 10 times2 the maximum daily total human dose (on a mg/kg basis). At this dose, peak plasma levels obtained in monkeys were approximately 2 times those obtained in humans. There has been no evidence of a teratogenic effect in any of the animal species tested (rat, rabbit, mouse, monkey) at 6-50 times the maximum daily human dose (on a mg/kg basis). There are, however, no adequate and well-controlled studies in pregnant women. Norfloxacin should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.

    Nursing mothers

    It is not known whether norfloxacin is excreted in human milk.

    When a 200 mg dose of Noroxin was administered to nursing mothers, norfloxacin was not detected in human milk. However, because the dose studied was low, because other drugs in this class are secreted in human milk, and because of the potential for serious adverse reactions from norfloxacin in nursing infants, a decision should be made to discontinue nursing or to discontinue the drug, taking into account the importance of the drug to the mother.

    Pediatric use

    The safety and effectiveness of oral norfloxacin in pediatric patients and adolescents below the age of 18 years have not been established. Norfloxacin causes arthropathy in juvenile animals of several animal species.

    Geriatric use

    Geriatric patients are at increased risk for developing severe tendon disorders including tendon rupture when being treated with a fluoroquinolone such as Noroxin. This risk is further increased in patients receiving concomitant corticosteroid therapy. Tendinitis or tendon rupture can involve the Achilles, hand, shoulder, or other tendon sites and can occur during or after completion of therapy; cases occurring up to several months after fluoroquinolone treatment have been reported. Caution should be used when prescribing Noroxin (Norfloxacin) to elderly patients, especially those on corticosteroids. Patients should be informed of this potential side effect and advised to discontinue Noroxin and contact their healthcare provider if any symptoms of tendinitis or tendon rupture occur.


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    Here is a list of popular medications containing norfloxacin as a main active pharmaceutical ingredient; their trade names, forms, doses, companies - manufacturers, distributors, suppliers, researchers and developers:

    Trade name of the drug Pharmaceutical forms and doses Companies
    Baccidal
  • Capsules; Oral; Norfloxacin 200 mg
  • Powder for Suspension; Oral; Norfloxacin 100 mg / 5 ml
  • Tablets; Oral; Norfloxacin 50 mg
  • Tablets; Oral; Norfloxacin 100 mg
  • Tablets; Oral; Norfloxacin 200 mg
  • Tablets; Oral; Norfloxacin 400 mg
  • Abbott
  • Chong Kun Dang Pharmaceutical
  • Gray's Pharmaceuticals
  • Kyorin Pharmaceutical
  • Shinlin Sinseng Pharmaceutical
  • Noroxin
  • Solution; Ophthalmic; Norfloxacin 0.3%
  • Tablets, Film-Coated; Oral; Norfloxacin 400 mg
  • Merck
  • Dynamic Laboratories
  • Farmila-Thea Farmaceutici
  • OBS Healthcare
  • Shire
  • Urobacid
  • Suspension; Oral; Norfloxacin 100 mg / 5 ml
  • Syrup; Oral; Norfloxacin 100 mg / 5 ml
  • Tablets, Film-Coated; Oral; Norfloxacin 400 mg
  • Novartis
  • Biochemie
  • F.P. Marketing
  • IDS Group
  • Medical Supplies
  • Sandoz
  • Sigma Laboratories
  • Svizera Healthcare
  • Tyrol Pharma